Configuratio quinque axis machinae CNC determinat quam duos ex tres axis rotationis utilizat et coniunctiones arbitrariis AB, AC, aut BC, dependant a type quinque axis machinae. Common types include ear axis machines and rotary machines.

Ear axis machines operate on the A axis (rotating around the X axis) and C axis (rotating around the Z axis), while rotary machines operate on the B axis (rotating around the Y axis) and C axis (rotating around the Z axis). The rotation axis in ear axis machines is indicated by the movement of the worktable, while rotary machines indicate their rotation axis by rotating the spindle.